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There has been continual progress in expanding immunization programs over time, but even before the COVID-19 pandemic, tens of millions of children worldwide were not receiving basic doses of vaccines. New research finds that there continue to be significant disparities in childhood vaccination, and poorer children from under-represented and minority groups in most countries are

Through small, neighborhood classes, researchers at UPMC Children’s Hospital of Pittsburgh and Promundo-US significantly reduced sexual violence among teenage boys living in areas of concentrated disadvantage. The study, published today in JAMA, is the culmination of a large Centers for Disease Control and Prevention clinical trial spanning 20 racially segregated neighborhoods in the Pittsburgh area

Pregnant women may be especially vulnerable to developing more severe cases of COVID-19 following SARS-CoV-2 infection, but little is known about their anti-SARS-CoV-2 immune response or how it may affect their offspring. In a study published in JAMA Network Open, a group led by investigators at Massachusetts General Hospital (MGH) provides new insights that could

COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study by researchers at Stanford Medicine. The findings identify new links between the course of the disease and a patient’s immune response.

One of the most recognizable characteristics of autism is an amazing diversity of associated behavioral symptoms. Clinicians view autism as a broad spectrum of related disorders, and the origin of the disease’s heterogeneity has puzzled scientists, doctors, and affected families for decades. In a recent study, researchers at Columbia University Vagelos College of Physicians and

Recent analyses indicate that pregnant women and newborns may face elevated risks of developing more severe cases of COVID-19 following SARS-CoV-2 infection. New research led by investigators at Massachusetts General Hospital (MGH) and published in Cell reveals lower than expected transfer of protective SARS-CoV-2 antibodies via the placenta from mothers who are infected in the

Substances present in cooked meats are associated with increased wheezing in children, Mount Sinai researchers report. Their study, published in Thorax, highlights pro-inflammatory compounds called advanced glycation end-products (AGEs) as an example of early dietary risk factors that may have broad clinical and public health implications for the prevention of inflammatory airway disease. Asthma prevalence

Black children are removed from their families at much greater rates than any other race or ethnicity in this country. At the same time the sheer number of all child abuse investigations in the US is staggering: experts estimate that by age 18 one out of three children has been the subject of a child

Results of a national study show significant sex and age-based differences among youth and young adults who experience a nonfatal opioid overdose. Female youth between the ages of 11 and 16 have a higher incidence of nonfatal opioid overdose compared to male youth of the same age. That reverses at age 17, however, as males

Giving antimalarial medicines to children monthly during the rainy season cut malaria deaths in children by 42 per cent, making a case for wide implementation in malaria-endemic African regions, a study found. In 2012, the World Health Organization (WHO) issued guidelines for implementing intermittent monthly drug administration, also known as Seasonal Malaria Chemoprevention (SMC), in

For the first time in the world, the humanoid robot iCub, developed and built by researchers at IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology), enters a rehabilitation facility to take part in an experimental therapy to treat cognitive impairments in children with autism spectrum condition. The experimental protocol has been defined by the IIT

A new study looking at the results of testing children for COVID-19 through a Children’s National Hospital community-based testing site found that one in four patients had a positive test. The findings, reported online Dec. 18 in The Journal of Pediatrics, reinforce that children and young adults are impacted by the virus more than originally

Children of mothers who drink relatively more cow’s milk during breastfeeding are at reduced risk of developing food allergies. That is the conclusion of researchers from Chalmers University of Technology, Sweden, in a new study published in the scientific journal Nutrients. The result is based on a survey of more than 500 Swedish women’s eating

In spring 2020, when soccer and sports clubs closed for sever-al weeks due to the Corona pandemic, children and adoles-cents looked for alternative physical activities. According to a supplementary study covering more than 1700 children and adolescents aged from 4 to 17 as part of the Motorik-Modul Study (MoMo) conducted by Karlsruhe Institute of Technology

Invirsa, a Columbus-based pharmaceutical company, today announced execution of a license agreement with the Abigail Wexner Research Institute (AWRI) at Nationwide Children’s Hospital as Invirsa seeks to broaden its treatment platform to address respiratory diseases. The announcement coincides with Invirsa’s securing a $16.9 million contract from the government agency involved in the development of medical

Two groundbreaking studies at the UC Davis MIND Institute provide clues about possible types of autism linked to brain structure, including size and white matter growth. The research is based on brain scans taken over many years as part of the Autism Phenome Project (APP) and Girls with Autism, Imaging of Neurodevelopment (GAIN) studies. It

Scientists at the University of Exeter have identified a way to “rescue” cells that have genetically mutated, paving the way to a possible new treatment for rare terminal childhood illness such as mitochondrial disease. The research, funded by the United Mitochondrial Disease Foundation in the USA, was led by Professors Matt Whiteman and Tim Etheridge.

The growth of prenatal screening in Europe has reduced the number of babies being born per year with Down syndrome (DS) by an average of 54%, according to a new study published in the European Journal of Human Genetics by researchers from Massachusetts General Hospital (MGH) and international Down syndrome organizations. In research published in

Parents, caregivers and health care professionals are increasingly concerned about childhood obesity. Compounding their concern are fears of inadvertently provoking disordered eating, such as unhelpful dieting, when discussing a child’s weight status (i.e. normal weight, overweight or obese). Given the complexity of these concerns, major health advocacy groups have independently published guidelines for having conversations

At the beginning of the coronavirus disease 2019 (COVID-19) pandemic, many scientists were left baffled about why and how the illness predominantly affected older adults and those with comorbidities. These groups are at a higher risk of developing severe symptoms and are more likely to die from the infection. Meanwhile, most children and young people

An observational study has launched to evaluate the short- and long-term health outcomes of SARS-CoV-2 infection in children, including multisystem inflammatory syndrome in children (MIS-C), and to characterize the immunologic pathways associated with different disease presentations and outcomes. SARS-CoV-2 is the virus that causes COVID-19. The study, called the Pediatric Research Immune Network on SARS-CoV-2

Mortality rates among young adults are rising in the U.S. due in part to “deaths of despair” — preventable deaths from suicide, drug overdoses and alcohol-related liver disease. An intensive childhood intervention program called Fast Track could help reduce these deaths by reducing risky behaviors in adolescence and young adulthood, finds new research from Duke

One consequence of the COVID-19 pandemic is that more families are putting off their children’s preventive care visits, causing pediatric providers to worry about missed vaccines. In a recent study published in Pediatrics, researchers at Nationwide Children’s Hospital evaluated changes in measles vaccination rates from before the pandemic to this summer, when return for clinical

The bacteria Streptococcus pneumoniae colonizes the nasopharynx and can cause pneumonia. Then, it can spread from the lungs to the bloodstream and cause organ damage. This opportunistic pathogen commonly infects young children, those who are immunocompromised and the elderly. In 2015, S. pneumoniae infections worldwide killed an estimated 192,000 to 366,000 children under age 5.

Research has shown that human milk is the optimal nutrition source for neonates and infants. It confers protection against both immediately life-threatening infant diseases such as necrotizing enterocolitis, as well as later onset diseases in adults, like obesity, diabetes and inflammatory bowel disease. Scientific evidence suggests that what a mother eats while she is breastfeeding

Sledding is a popular winter activity in communities across the country, but it may not be as risk-free as many people think. A new study conducted by researchers at the Center for Injury Research and Policy at Nationwide Children’s Hospital found that 220,488 patients were treated in U.S. emergency departments for injuries related to sledding